Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337295 | 0.84 | APP (0.62) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL11667730 | 0.82 | MEN1 (0.55) | LMNACA1CA2CA4CA6 | |
| SCHEMBL23214335 | 0.78 | IAPP (0.57) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL28112300 | 0.78 | APP (0.44) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL28209720 | 0.77 | ALDH1A1 (0.69) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL6910501 | 0.77 | CYP1A2 (0.51) | POLBALDH1A1 | |
| SCHEMBL10718079 | 0.77 | KDM4E (0.50) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL7092605 | 0.77 | CYP3A4 (0.56) | KDM4EHIF1AHSD17B10TDP1LMNA | |
| SCHEMBL338280 | 0.76 | ALDH1A1 (0.68) | TDP1LMNAPOLBCA1CA2 | |
| SCHEMBL28665104 | 0.76 | ALOX15 (0.46) | KDM4EHIF1AHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101497567-B | Preparation of caffeic acid 3,4-dihydroxyphenyl ethyl ester and its derivative phenyl acrylic acid phenyl alkyl ester compound | ZHIZHEN ZHANG | 2012-07-25 | — | — | CN | disclosed |
| CN-101497567-A | Preparation of 3-(3,4-dihydroxyphenyl)-acrylic acid 2-(3,4-dihydroxyphenyl)-ethyl ester and derivative phenyl acrylic acid phenyl alkyl ester compound | ZHIZHEN ZHANG (CN) | 2009-08-05 | — | — | CN | disclosed |