Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 19/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 13/20 | 0.59 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819749 | 1.00 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL3820124 | 0.94 | ITGA4 (0.55) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL4139238 | 0.91 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL3832342 | 0.87 | ITGA4 (0.54) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL3829907 | 0.86 | ALDH1A1 (0.55) | ITGB1ITGA4ITGB7ITGA2L3MBTL1 | |
| SCHEMBL3835432 | 0.86 | ITGB1 (0.52) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL4144035 | 0.85 | ITGA4 (0.54) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL3834136 | 0.85 | ITGA4 (0.52) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL3837327 | 0.85 | ITGA4 (0.53) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL3831343 | 0.85 | ITGB1 (0.51) | ITGB1ITGA4ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360711-A | L-phenylalanine derivatives and its application as integrin antagonists | ASTRAZENECA AB (SE) | 2009-02-04 | — | — | CN | claimed |
| CN-101360711-A | L-phenylalanine derivatives and its application as integrin antagonists | ASTRAZENECA AB (SE) | 2009-02-04 | — | — | CN | disclosed |