Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789132 | 0.90 | PROKR1 (0.38) | PROKR1FPR2CNR2MEN1KMT2A | |
| SCHEMBL2790497 | 0.89 | PROKR1 (0.45) | PROKR1CNR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL2789452 | 0.89 | PROKR1 (0.45) | PROKR1CNR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL2789222 | 0.89 | PROKR1 (0.41) | PROKR1FPR2CNR2SMN1; SMN2HPGD | |
| SCHEMBL7902566 | 0.88 | PROKR1 (0.38) | PROKR1CNR2MEN1KMT2APER2 | |
| SCHEMBL2788344 | 0.86 | PROKR1 (0.38) | PROKR1CNR2ALDH1A1MAPTTSHR | |
| SCHEMBL2791611 | 0.86 | PROKR1 (0.41) | PROKR1FPR2CNR2SMN1; SMN2RAB9A | |
| SCHEMBL2790512 | 0.85 | PROKR1 (0.42) | PROKR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2814775 | 0.85 | PROKR1 (0.37) | PROKR1FPR2CNR2MEN1KMT2A | |
| SCHEMBL2814776 | 0.85 | PROKR1 (0.37) | PROKR1FPR2CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |