Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129386 | 0.71 | LMNA (0.44) | KMT2AALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL2128489 | 0.71 | MAPT (0.48) | KMT2AALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6755746 | 0.70 | POLB (0.53) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11544080 | 0.69 | ALDH1A1 (0.60) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Dinitrophenylene SCHEMBL28013915 | 0.68 | SMN1; SMN2 (0.58) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27903552 | 0.67 | ALDH1A1 (0.50) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9593080 | 0.67 | MAPT (0.53) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6756625 | 0.66 | TP53 (0.45) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5173228 | 0.65 | MAPK13 (0.61) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11541402 | 0.65 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511813-A | Heterocyclic FXR binding compounds | PHENEX PHARMACEUTICALS AG (DE) | 2009-08-19 | — | — | CN | disclosed |