Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836616 | 0.89 | MEN1 (0.34) | THRBTP53POLBMAPTGRM1 | |
| SCHEMBL1640301 | 0.77 | F10 (0.39) | RXFP1 | |
| SCHEMBL3835105 | 0.76 | ROCK2 (0.36) | — | |
| SCHEMBL3839792 | 0.75 | EGFR (0.34) | THRBTP53POLBMAPTGRM1 | |
| SCHEMBL3834826 | 0.72 | F10 (0.34) | — | |
| SCHEMBL3837178 | 0.70 | P2RY12 (0.40) | GRM1 | |
| SCHEMBL3836854 | 0.70 | EGFR (0.36) | TP53MAPTGRM1 | |
| SCHEMBL3840536 | 0.66 | F10 (0.33) | MEN1KMT2A | |
| SCHEMBL3833858 | 0.65 | CYP11B1 (0.40) | POLB | |
| SCHEMBL1640705 | 0.65 | F10 (0.36) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101534832-A | Substituted nitrogen containing heterocycles as platelet ADP receptor inhibitors | PORTOLA PHARM INC (US) | 2009-09-16 | — | — | CN | disclosed |