Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | KLK1 | P06870 | 2/20 | 0.48 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593172 | 0.86 | MAPT (0.74) | POLBCA1CA2CA4CA7 | |
| SCHEMBL10603962 | 0.85 | POLB (0.67) | POLBCA1CA2CA4CA7 | |
| SCHEMBL7055067 | 0.83 | POLB (0.70) | POLBCA1CA2CA4CA7 | |
| SCHEMBL1189878 | 0.83 | CA12 (0.59) | POLBCA1CA2MAPTKDM4E | |
| SCHEMBL1146000 | 0.82 | SMN1; SMN2 (0.59) | POLBCA1CA2CA4CA7 | |
| SCHEMBL5348324 | 0.82 | LOXL2 (0.51) | POLBTSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL27966406 | 0.81 | GAA (0.67) | CA1CA2CA7MAPTMEN1 | |
| SCHEMBL8751494 | 0.81 | CA1 (0.64) | POLBCA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL8649176 | 0.81 | SMN1; SMN2 (0.57) | CA1CA2CA4CA7MAPT | |
| Hydrochloric Acid SCHEMBL5348319 | 0.81 | KLKB1 (0.50) | POLBTSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101407484-A | Method for synthesizing beta-carbonyl thioacid amide compound | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-04-15 | — | — | CN | disclosed |