Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716193 | 0.92 | PPARG (0.52) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL8332027 | 0.91 | PPARG (0.64) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL27746688 | 0.89 | NR4A1 (0.55) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL7167438 | 0.88 | MAOB (0.58) | NR4A1NR4A2NR4A3FFAR1LMNA | |
| SCHEMBL8871420 | 0.87 | LMNA (0.64) | PPARGPPARAFFAR1FFAR4LMNA | |
| SCHEMBL8865699 | 0.86 | PPARG (0.63) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL27383580 | 0.86 | NR4A1 (0.55) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL14021577 | 0.83 | LMNA (0.62) | PPARGPPARAFFAR1FFAR4LMNA | |
| SCHEMBL7908556 | 0.83 | MAOB (0.56) | PPARGPPARANR4A1NR4A2NR4A3 | |
| SCHEMBL27757352 | 0.82 | LMNA (0.51) | PPARGPPARANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346358-A | Estrogen modulators | PFIZER PROD INC (US) | 2009-01-14 | — | — | CN | disclosed |