Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752987 | 0.84 | ALDH1A1 (0.51) | CYP1A2CYP2C19PPARGPPARALTA4H | |
| SCHEMBL28779136 | 0.82 | PPARG (0.60) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8332027 | 0.82 | PPARG (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27608802 | 0.78 | EPHX1 (0.45) | SLC6A3PPARGPPARAHTT | |
| SCHEMBL27628157 | 0.78 | EPHX1 (0.45) | RAB9ANPC1 | |
| SCHEMBL8865699 | 0.78 | PPARG (0.63) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8871420 | 0.76 | LMNA (0.64) | LMNAPPARGPPARALTA4HFFAR1 | |
| SCHEMBL27757335 | 0.75 | LMNA (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27716193 | 0.75 | PPARG (0.52) | PPARGPPARASMN1; SMN2NPC1FFAR1 | |
| SCHEMBL27757334 | 0.75 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346358-A | Estrogen modulators | PFIZER PROD INC (US) | 2009-01-14 | — | — | CN | disclosed |