Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993289 | 0.94 | ALDH1A1 (0.65) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| Fluorobenzene SCHEMBL28353608 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| SCHEMBL29443997 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HPGDBCL2L1HSD17B10NPC1 | |
| SCHEMBL714236 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HPGDBCL2L1HSD17B10NPC1 | |
| SCHEMBL18189724 | 0.79 | ALDH1A1 (0.79) | ALDH1A1HPGDBCL2L1HSD17B10NPC1 | |
| SCHEMBL28248560 | 0.75 | MAOA (0.43) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| SCHEMBL31166650 | 0.75 | BCL2L1 (0.71) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| SCHEMBL3681826 | 0.75 | ALDH1A1 (0.90) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| SCHEMBL250077 | 0.75 | BCL2L1 (0.71) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 | |
| 2-Phenylphenol SCHEMBL9135662 | 0.75 | HPGD (0.90) | ALDH1A1HPGDBCL2L1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101423511-A | Ezetimibe intermediate and synthesis method of Ezetimibe | ZHONGSHAN YI ANTAI PHARMACEUTI (CN) | 2009-05-06 | — | — | CN | disclosed |