SCHEMBL28779264

SCHEMBL28779264

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(F)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.71
LMNA P02545 3/20 0.70
KMT2A Q03164 4/20 0.70
MEN1 O00255 3/20 0.70
RAB9A P51151 3/20 0.66
GAA P10253 1/20 0.66
L3MBTL1 Q9Y468 2/20 0.60
ALDH1A1 P00352 2/20 0.60
TSHR P16473 1/20 0.60
CA12 O43570 2/20 0.59
CA9 Q16790 2/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA13 Q8N1Q1 1/20 0.59
CA14 Q9ULX7 1/20 0.59
PPARG P37231 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241750 0.90 LMNA (0.80) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL5184916 0.87 LMNA (0.76) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL6465683 0.85 LMNA (0.72) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL29445562 0.85 LMNA (0.72) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL5184926 0.85 LMNA (0.72) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL5185918 0.85 LMNA (0.72) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL1395598 0.85 LMNA (0.72) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL5184894 0.84 LMNA (0.70) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL20504291 0.84 LMNA (0.70) TP53LMNAKMT2AMEN1RAB9A
SCHEMBL8418023 0.84 LMNA (0.70) TP53LMNAKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761379-A Color-developing agent and heat-sensitive recording material 三菱化学株式会社 2022-07-15 CN disclosed