SCHEMBL6465683

SCHEMBL6465683

Cc1ccc(S(=O)(=O)NC(=O)Nc2cccc(O)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.72
KMT2A Q03164 2/20 0.66
MEN1 O00255 1/20 0.64
CA12 O43570 2/20 0.60
CA9 Q16790 2/20 0.60
TP53 P04637 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA4 P22748 1/20 0.60
CA6 P23280 1/20 0.60
CA5A P35218 1/20 0.60
CA7 P43166 1/20 0.60
CA13 Q8N1Q1 1/20 0.60
CA14 Q9ULX7 1/20 0.60
NLRP3 Q96P20 3/20 0.60
PPARG P37231 1/20 0.58
RAB9A P51151 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
NR2E3 Q9Y5X4 1/20 0.58
NCOR2 Q9Y618 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445562 1.00 LMNA (0.72) LMNAKMT2AMEN1CA12CA9
SCHEMBL6241750 0.91 LMNA (0.80) LMNAKMT2AMEN1CA12CA9
SCHEMBL5184916 0.89 LMNA (0.76) LMNAKMT2AMEN1CA12CA9
SCHEMBL28703444 0.87 LMNA (0.60) LMNAKMT2AMEN1CA12CA9
SCHEMBL5184926 0.86 LMNA (0.72) LMNAKMT2AMEN1CA12CA9
SCHEMBL1395598 0.86 LMNA (0.72) LMNAKMT2AMEN1CA12CA9
SCHEMBL5185918 0.86 LMNA (0.72) LMNAKMT2AMEN1CA12CA9
SCHEMBL28779264 0.85 TP53 (0.71) LMNAKMT2AMEN1CA12CA9
SCHEMBL20504291 0.85 LMNA (0.70) LMNAKMT2AMEN1CA12CA9
SCHEMBL29771220 0.85 LMNA (0.70) LMNAKMT2AMEN1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105833-B Preparation method of high-whiteness thermosensitive color-developing agent containing sulfonylurea structure 河北建新化工股份有限公司 2023-09-05 CN claimed
CN-113929602-A Method for preparing N- [ (m-hydroxyphenyl) carbamoyl ] p-methylbenzenesulfonamide and application thereof 南通沃兰化工有限公司 2022-01-14 CN claimed
CN-114105833-B Preparation method of high-whiteness thermosensitive color-developing agent containing sulfonylurea structure 河北建新化工股份有限公司 2023-09-05 CN disclosed
CN-114105833-B Preparation method of high-whiteness thermosensitive color-developing agent containing sulfonylurea structure 河北建新化工股份有限公司 2023-09-05 CN disclosed
CN-113929602-A Method for preparing N- [ (m-hydroxyphenyl) carbamoyl ] p-methylbenzenesulfonamide and application thereof 南通沃兰化工有限公司 2022-01-14 CN disclosed
CN-113929602-A Method for preparing N- [ (m-hydroxyphenyl) carbamoyl ] p-methylbenzenesulfonamide and application thereof 南通沃兰化工有限公司 2022-01-14 CN disclosed
CN-113929602-A Method for preparing N- [ (m-hydroxyphenyl) carbamoyl ] p-methylbenzenesulfonamide and application thereof 南通沃兰化工有限公司 2022-01-14 CN disclosed
CN-107311893-B The synthetic method of temperature-sensitive sensitizer N- tolysulfonyl-N '-(3- tolysulfonyl phenyl) urea 耿潇 2018-11-09 CN disclosed
CN-107311893-B The synthetic method of temperature-sensitive sensitizer N- tolysulfonyl-N '-(3- tolysulfonyl phenyl) urea 耿潇 2018-11-09 CN disclosed
CN-107311893-A The synthetic method of temperature-sensitive sensitizer N tolysulfonyl N ' (3 tolysulfonyl phenyl) urea 耿潇 2017-11-03 CN disclosed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed