SCHEMBL28779455

SCHEMBL28779455

CCOC(CC)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
KCNH2 Q12809 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
PPARG P37231 4/20 0.44
PPARA Q07869 3/20 0.44
PPARD Q03181 1/20 0.44
LMNA P02545 3/20 0.44
HSD17B10 Q99714 2/20 0.44
MDM2 Q00987 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL926833 0.88 PGR (0.44) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL633438 0.85 PGR (0.50) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL14359118 0.84 MDM2 (0.56) PPARGPPARAPPARDMDM2
SCHEMBL28971849 0.83 PGR (0.49) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL11522787 0.83 PGR (0.49) PGRADRA2AADRA2BHTR2AHRH1
Hydrochloric Acid SCHEMBL27261596 0.83 PGR (0.49) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL29549835 0.83 LMNA (0.45) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL8758263 0.83 PRSS1 (0.47) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL5168028 0.82 PGR (0.52) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL23238 0.82 PGR (0.52) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591232-A Long-acting control agent for ectoparasites of animals 三井化学AGRO株式会社 2022-06-07 CN disclosed