Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 10/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL29058085 | 1.00 | LMNA (0.59) | LMNAALDH1A1ALOX15HSD17B10FFAR3 | |
| Acrylic Acid SCHEMBL15676628 | 1.00 | LMNA (0.59) | LMNAALDH1A1ALOX15HSD17B10FFAR3 | |
| Acrylic Acid SCHEMBL11693557 | 0.92 | ALDH1A1 (0.61) | LMNAALDH1A1ALOX15HSD17B10FFAR3 | |
| Acrylic Acid SCHEMBL28630391 | 0.91 | LMNA (0.62) | LMNAALDH1A1ALOX15HSD17B10FFAR3 | |
| Acrylic Acid SCHEMBL36466 | 0.91 | — | — | |
| Acrylic Acid SCHEMBL15955850 | 0.91 | LMNA (0.71) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL29457256 | 0.91 | LMNA (0.71) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL11406925 | 0.91 | LMNA (0.71) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL2524668 | 0.91 | LMNA (0.71) | LMNAALDH1A1ALOX15HSD17B10TSHR | |
| Acrylic Acid SCHEMBL29707305 | 0.91 | LMNA (0.71) | LMNAALDH1A1ALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716878-A | Solvent-free UV gloss oil and preparation and use methods thereof | 张家港保税区康得菲尔实业有限公司 | 2022-07-08 | — | — | CN | disclosed |