Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748380 | 0.78 | CHEK1 (0.45) | NR4A2IDO1PTPN1KDM4EGABRA1 | |
| SCHEMBL19988801 | 0.72 | KDM4E (0.47) | MAP2K1NR4A2CREBBPIDO1PTPN1 | |
| SCHEMBL29520873 | 0.71 | KDM4E (0.45) | MAP2K1NR4A2CREBBPKDM4EGABRA1 | |
| SCHEMBL812065 | 0.71 | KDM4E (0.59) | MAP2K1KDM4ELMNAPKMALDH1A1 | |
| SCHEMBL27918837 | 0.70 | NR4A2 (0.49) | NR4A2KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL11117588 | 0.69 | TUBB4A (0.51) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL3834924 | 0.69 | NR4A2 (0.49) | MAP2K1NR4A2KDM4EPKMALDH1A1 | |
| SCHEMBL27312758 | 0.69 | KDM4E (0.57) | KDM4ELMNAPKMALDH1A1MAPT | |
| SCHEMBL11119591 | 0.69 | CHEK1 (0.41) | NR4A2KDM4EGABRA1GABRG2GABRB3 | |
| SCHEMBL11122004 | 0.68 | CHEK1 (0.43) | NR4A2IDO1PTPN1KDM4EGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101578100-A | Use of neuroprotective compounds for obtaining drugs for treating neurodegenerative diseases | SERVIER LAB (FR) | 2009-11-11 | — | — | CN | disclosed |