SCHEMBL29520873

SCHEMBL29520873

COC(=O)c1cccnc1-c1nccc2c1c(=O)[nH]c1ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.45
▸ ALDH1A1 P00352 3/20 0.45
▸ HPGD P15428 3/20 0.45
▸ HSD17B10 Q99714 3/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ PARP1 P09874 3/20 0.45
▸ MAP2K1 Q02750 1/20 0.44
▸ LMNA P02545 2/20 0.44
▸ MAPT P10636 2/20 0.44
▸ GABRP O00591 1/20 0.44
▸ GABRD O14764 1/20 0.44
▸ PDE5A O76074 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ GABRA1 P14867 1/20 0.44
▸ GABRB1 P18505 1/20 0.44
▸ GABRG2 P18507 1/20 0.44
▸ GABRB3 P28472 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19988801 0.78 KDM4E (0.47) KDM4EALDH1A1HPGDHSD17B10MAP2K1
SCHEMBL812065 0.75 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL28781507 0.71 MAP2K1 (0.45) KDM4EALDH1A1HPGDHSD17B10MAP2K1
SCHEMBL27312758 0.70 KDM4E (0.57) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL7649536 0.69 TDP1 (0.59) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL5080656 0.69 BCHE (0.55) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL3454207 0.68 AURKA (0.58) KDM4EMAP2K1NR4A2CREBBPAURKA
SCHEMBL29960343 0.68 TDO2 (0.63) MAPK1PARP14KIF11
SCHEMBL15133535 0.68 MAP2K1 (0.44) KDM4EALDH1A1HPGDHSD17B10MAP2K1
Hydrochloric Acid SCHEMBL27734884 0.68 BCHE (0.54) KDM4EALDH1A1HPGDHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122017736-A Relative motion positioning method, system, device, medium and product of multi-submarine beacon network 中国人民解放军61540部队 2026-05-12 — — CN claimed
CN-115928301-A Biodegradable single-side weft-knitted fabric with hidden transverse bar mesh effect and production method thereof 泉州海天材料科技股份有限公司 2023-04-07 — — CN claimed
CN-122017736-A Relative motion positioning method, system, device, medium and product of multi-submarine beacon network 中国人民解放军61540部队 2026-05-12 — — CN disclosed
WO-2025069165-A1 MULTICORE OPTICAL FIBER 日本電信電話株式会社 2025-04-03 — — WO disclosed
EP-4463482-A1 VEGF AND TIE2-BINDING FUSION PROTEIN AND USES THEREOF Ingenia Therapeutics Inc. (US) 2024-11-20 — — EP disclosed
CN-221995041-U J-shaped pipe submarine cable protection mechanism 浙江征予新能源集团股份有限公司 2024-11-12 — — CN disclosed
CN-118922443-A Fusion proteins binding VEGF and Tie2 and uses thereof 英格尼亚治疗公司 2024-11-08 — — CN disclosed
WO-2024225884-A1 PASSENGER PROTECTION DEVICE FOR VEHICLE 아우토리브 디벨롭먼트 아베 2024-10-31 — — WO disclosed
CN-221709383-U I-shaped pipe submarine cable protection mechanism 浙江征予新能源集团股份有限公司 2024-09-13 — — CN disclosed
US-20230287109-A1 VEGF and TIE2-Binding Fusion Protein and Uses Thereof INGENIA THERAPEUTICS INC. (US) 2023-09-14 — — US disclosed
WO-2023137395-A1 VEGF AND TIE2-BINDING FUSION PROTEIN AND USES THEREOF INGENIA THERAPEUTICS INC. (US) 2023-07-20 — — WO disclosed
WO-2022054336-A1 STEEL PIPE COLLAPSE STRENGTH PREDICTION MODEL GENERATION METHOD, STEEL PIPE COLLAPSE STRENGTH PREDICTION METHOD, STEEL PIPE MANUFACTURING CHARACTERISTICS DETERMINATION METHOD, AND STEEL PIPE MANUFACTURING METHOD JFEスチール株式会社 2022-03-17 — — WO disclosed
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