Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679635 | 0.86 | AKR1C3 (0.49) | ALDH1A1HPGDKDM4EHSD17B10GRM1 | |
| SCHEMBL9345918 | 0.85 | AKR1C3 (0.51) | ALDH1A1HPGDKDM4EHSD17B10CYP2C9 | |
| SCHEMBL30953697 | 0.83 | PLG (0.54) | ALDH1A1HPGDKDM4EHSD17B10GRM1 | |
| SCHEMBL1261130 | 0.83 | PLG (0.54) | ALDH1A1HPGDKDM4EHSD17B10GRM1 | |
| SCHEMBL32660739 | 0.81 | TDP1 (0.55) | KDM4EHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL490579 | 0.81 | TDP1 (0.55) | KDM4EHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL27449783 | 0.80 | HPGD (0.53) | ALDH1A1HPGDKDM4EHSD17B10GRM1 | |
| SCHEMBL28183228 | 0.79 | TDP1 (0.53) | KDM4EHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL4066823 | 0.78 | PTGS1 (0.62) | CYP2C9MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL13898612 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |