Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.54 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TYR | P14679 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261130 | 1.00 | PLG (0.54) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL29495445 | 0.84 | HSP90AA1 (0.60) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL1546509 | 0.84 | ALDH1A1 (0.62) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL2354241 | 0.84 | HSP90AA1 (0.60) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL2878153 | 0.83 | ALDH1A1 (0.49) | PTGS1ALDH1A1HPGDCYP3A4MAPK1 | |
| SCHEMBL28571178 | 0.82 | TRPA1 (0.52) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL14162932 | 0.82 | TRPA1 (0.57) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL13898612 | 0.82 | ALDH1A1 (0.53) | PLGKLK1KLK6ALDH1A1HPGD | |
| SCHEMBL16229424 | 0.80 | FABP3 (0.47) | PLGKLK1KLK6TRPA1PTGS1 | |
| SCHEMBL12270315 | 0.80 | TRPA1 (0.48) | PLGKLK1KLK6TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |