Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 0.82 | TSHR (0.57) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| SCHEMBL1679019 | 0.82 | TSHR (0.57) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 0.82 | TSHR (0.57) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28219889 | 0.81 | TSHR (0.55) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL11491904 | 0.81 | TSHR (0.55) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL27627315 | 0.79 | TSHR (0.53) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL4595511 | 0.76 | GAA (0.51) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| SCHEMBL1143951 | 0.76 | TSHR (0.50) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| SCHEMBL4679974 | 0.75 | GRIN2B (0.55) | KMT2AKDM4EPOLBSMN1; SMN2GAA | |
| Dl-Phenylalanine SCHEMBL27693339 | 0.75 | ALPI (0.54) | KMT2AKDM4EPOLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121433-B | Synthesis method of N-8-quinolyl-2-aminobenzamide compound | 信阳师范学院 | 2022-07-15 | — | — | CN | disclosed |