Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750210 | 0.91 | HTR6 (0.43) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL3626402 | 0.79 | HTR6 (0.62) | HTR6CYP3A4CYP2D6DRD3KCNH2 | |
| SCHEMBL28781697 | 0.75 | HTR6 (0.41) | HTR6CYP3A4CYP2D6KCNH2HTR2A | |
| SCHEMBL27785794 | 0.72 | MCOLN3 (0.43) | HTR6CYP3A4CYP2D6DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL3623671 | 0.72 | HTR6 (0.56) | HTR6CYP3A4CYP2D6DRD3KCNH2 | |
| SCHEMBL3623255 | 0.70 | HTR6 (0.64) | HTR6CYP3A4CYP2D6DRD2DRD3 | |
| SCHEMBL27750208 | 0.67 | HTR6 (0.43) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3621706 | 0.65 | HTR6 (0.80) | HTR6CYP3A4CYP2D6DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL3623124 | 0.64 | HTR6 (0.57) | HTR6CYP3A4CYP2D6DRD3KCNH2 | |
| SCHEMBL27771179 | 0.63 | HTR6 (0.47) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |