Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781698 | 0.91 | HTR6 (0.41) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL3623255 | 0.78 | HTR6 (0.64) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL27750208 | 0.74 | HTR6 (0.43) | HTR6CYP3A4CYP2D6THRBMEN1 | |
| Trifluoroacetic Acid SCHEMBL3623124 | 0.71 | HTR6 (0.57) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL3626402 | 0.70 | HTR6 (0.62) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL27785767 | 0.69 | SLC6A3 (0.39) | MEN1USP2ALDH1A1MAPK1KMT2A | |
| SCHEMBL28781697 | 0.67 | HTR6 (0.41) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL27989535 | 0.66 | OPRD1 (0.45) | HTR6ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3623671 | 0.64 | HTR6 (0.56) | HTR6CYP3A4CYP2D6KCNH2 | |
| SCHEMBL27989543 | 0.64 | EP300 (0.33) | HTR6THRBALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |