Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819738 | 0.86 | KAT6A (0.50) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6911012 | 0.86 | SMN1; SMN2 (0.43) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19090371 | 0.84 | SMN1; SMN2 (0.50) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12221840 | 0.83 | CYP4F2 (0.51) | CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL28268128 | 0.83 | CYP4F2 (0.45) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL597591 | 0.82 | MAOB (0.49) | CYP4F2CYP4A11TDP1MRGPRX4 | |
| SCHEMBL3033628 | 0.82 | BCL2 (0.50) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30407967 | 0.82 | TDP1 (0.48) | CYP4F2CYP4A11TDP1L3MBTL1FOLH1 | |
| SCHEMBL8580572 | 0.82 | PRSS1 (0.46) | CYP4F2CYP4A11SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27458626 | 0.81 | LPL (0.53) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589037-A | Heteromonocyclic compounds and uses thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-11-25 | — | — | CN | disclosed |