Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319989 | 0.97 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL1332031 | 0.95 | GABRA1 (0.55) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL262868 | 0.95 | GABRA1 (0.55) | GABRA1GABRB2ATP4AATP4BPOLB | |
| Methane SCHEMBL28083182 | 0.92 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| Propane SCHEMBL27547406 | 0.92 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL28144550 | 0.92 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| Hydrochloric Acid SCHEMBL625383 | 0.92 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL28967677 | 0.92 | GABRA1 (0.52) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL350947 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2ATP4AATP4BPOLB | |
| SCHEMBL30303201 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2ATP4AATP4BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109701645-B | Catalyst composition and application thereof | 中国石油化工股份有限公司 | 2021-12-21 | — | — | CN | disclosed |