Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798521 | 0.92 | SLC6A2 (0.42) | ADRA1DADRA1AADRA1BSLC6A2SLC6A3 | |
| SCHEMBL20490485 | 0.81 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BMAPTKMT2A | |
| SCHEMBL28785764 | 0.78 | HDAC3 (0.45) | SLC6A2SLC6A3SLC6A4KMT2AHDAC3 | |
| Fluoride SCHEMBL28212837 | 0.76 | HTR7 (0.45) | ADRA1DADRA1AADRA1BSLC6A2SLC6A3 | |
| SCHEMBL28212829 | 0.76 | HTR7 (0.45) | ADRA1DADRA1AADRA1BSLC6A2SLC6A3 | |
| SCHEMBL2839221 | 0.76 | HDAC4 (0.58) | MAPTKMT2AUSP2ESR1NR4A1 | |
| SCHEMBL20490541 | 0.75 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BMAPTKMT2A | |
| SCHEMBL2837573 | 0.75 | HDAC4 (0.66) | ADRA1DADRA1AADRA1BMAPTKMT2A | |
| SCHEMBL20490299 | 0.75 | CHRNA7 (0.55) | ADRA1DADRA1AADRA1BMAPTKMT2A | |
| SCHEMBL2846604 | 0.74 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | disclosed |