SCHEMBL2878334

SCHEMBL2878334

Cc1cc(Cl)nc2cc3c(cc12)OC(C)(C)[C@H](O)[C@H]3NC(=O)OCCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.38
TAAR1 Q96RJ0 1/20 0.37
NAAA Q02083 1/20 0.36
ABCB1 P08183 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875735 0.92 ABCC9 (0.33)
SCHEMBL2008331 0.84 ABCB1 (0.43) KCNA5TAAR1ABCB1
SCHEMBL2881077 0.84 ABCB1 (0.43) KCNA5TAAR1ABCB1
SCHEMBL3596079 0.84 ABCB1 (0.43) KCNA5TAAR1ABCB1
SCHEMBL2008329 0.84 ABCB1 (0.43) KCNA5TAAR1ABCB1
SCHEMBL2013593 0.82 ABCB1 (0.41) KCNA5TAAR1ABCB1
SCHEMBL2873587 0.82 ABCB1 (0.41) KCNA5TAAR1ABCB1
SCHEMBL2009405 0.82 ABCB1 (0.53) KCNA5ABCB1
SCHEMBL2878735 0.82 ABCB1 (0.53) KCNA5ABCB1
SCHEMBL2878332 0.80 TAAR1 (0.46) KCNA5TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732929-B1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL IND LTD (JP) 2010-10-20 EP disclosed