Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768874 | 1.00 | LMNA (0.55) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL27907123 | 1.00 | LMNA (0.55) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL8894698 | 0.98 | LMNA (0.57) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL28574666 | 0.98 | LMNA (0.57) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL10354453 | 0.92 | — | — | |
| Adipic Acid SCHEMBL1147325 | 0.86 | LMNA (0.50) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL6913774 | 0.81 | — | — | |
| SCHEMBL3755409 | 0.81 | — | — | |
| SCHEMBL7408621 | 0.80 | TSHR (0.60) | LMNANFKB1TSHRPMP22FFAR4 | |
| SCHEMBL7928649 | 0.80 | TSHR (0.60) | LMNANFKB1TSHRPMP22FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101724670-B | Method for co-production of chiral hydroxy ester from uridine phosphinylidyne compounds | NANJING TECH UNIVERSITY (CN) | 2012-02-01 | — | — | CN | disclosed |
| CN-101693684-B | Method for preparing 4-hydroxylethylpyrrolidone-2-acetamide | SUZHOU HAOBO SCIENCE AND TECHNOLOGY CO LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-101724670-A | Method for co-production of chiral hydroxy ester from uridine phosphinylidyne compounds | NANJING UNIVERSITY OF TECHNOLOGY | 2010-06-09 | — | — | CN | disclosed |
| CN-101693684-A | Method for preparing 4-hydroxylethylpyrrolidone-2-acetamide | SUZHOU HAOBO SCIENCE AND TECHN | 2010-04-14 | — | — | CN | disclosed |