⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371925 | 1.00 | — | — | |
| SCHEMBL3755409 | 1.00 | — | — | |
| SCHEMBL10354453 | 0.83 | — | — | |
| SCHEMBL27768874 | 0.81 | LMNA (0.55) | — | |
| SCHEMBL28783402 | 0.81 | LMNA (0.55) | — | |
| SCHEMBL27907123 | 0.81 | LMNA (0.55) | — | |
| SCHEMBL8894698 | 0.79 | LMNA (0.57) | — | |
| SCHEMBL28574666 | 0.79 | LMNA (0.57) | — | |
| SCHEMBL11765423 | 0.79 | FOLH1 (0.55) | — | |
| SCHEMBL911280 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131279-B1 | INDUSTRIAL PROCESS FOR THE PRODUCTION OF L-CARNITINE | SIGMA TAU IND FARMACEUTI (IT) | 2004-05-12 | — | — | EP | disclosed |
| US-6566552-B2 | Reduction of an alkyl 4-chloro-3 -oxobutyrate or -oxobutyr amide to 4-chloro-3 -hydroxybutyrate or -hydroxybutyramide in the presence of ruthenium complex reduction catalyst followed by quaternization with trimethylamine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-05-20 | — | — | US | disclosed |
| US-20020165408-A1 | Industrial process for the production of L-carnitine | SIGMA-TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-11-07 | — | — | US | disclosed |
| EP-1131279-A1 | INDUSTRIAL PROCESS FOR THE PRODUCTION OF L-CARNITINE | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029370-A1 | INDUSTRIAL PROCESS FOR THE PRODUCTION OF L-CARNITINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-05-25 | — | — | WO | disclosed |