SCHEMBL28784149

SCHEMBL28784149

Cc1cc(C)cc(C(C)(C)C)c1.O=S(=O)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
POLB P06746 2/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 6/20 0.38
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B2 P37059 2/20 0.36
CA2 P00918 3/20 0.34
TYR P14679 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CA1 P00915 2/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
HTR1D P28221 1/20 0.34
ACLY P53396 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316288 0.84 TSHR (0.50) RXRARXRBPOLBTSHRALDH1A1
Formaldehyde SCHEMBL27921022 0.82 RXRB (0.46) RXRARXRBPOLBTSHRALDH1A1
SCHEMBL27310696 0.82 ALDH1A1 (0.44) TSHRALDH1A1KDM4ECA2CA1
SCHEMBL841739 0.82 ALDH1A1 (0.44) TSHRALDH1A1KDM4ECA2CA1
SCHEMBL1655430 0.79 GABRA1 (0.55) RXRARXRBPOLBTSHRALDH1A1
SCHEMBL11389703 0.77 LOX (0.42) RXRARXRBPOLBTSHRALDH1A1
SCHEMBL27826304 0.76 TSHR (0.71) TSHRALDH1A1KDM4EHSD17B2CA2
SCHEMBL14840527 0.76 RXRB (0.42) RXRARXRBPOLBTSHRALDH1A1
SCHEMBL12169374 0.76 LOX (0.44) RXRARXRBPOLBTSHRALDH1A1
SCHEMBL27312394 0.75 GABRA1 (0.46) RXRARXRBPOLBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101522611-B Substituted phenylsulfur trifluoride and other similar fluorinating agents UBE INDUSTRIES 2013-07-17 CN disclosed
CN-101522611-A Substituted phenylsulfur trifluoride and other similar fluorinating agents IM & T RES INC (US) 2009-09-02 CN disclosed