Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993777 | 1.00 | BRD4 (0.48) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL27784187 | 0.75 | VEGFA (0.43) | MEN1KMT2AHPGDHSD17B10CYP2D6 | |
| SCHEMBL27994026 | 0.75 | VEGFA (0.43) | MEN1KMT2AHPGDHSD17B10CYP2D6 | |
| SCHEMBL6736338 | 0.73 | LPO (0.32) | — | |
| SCHEMBL17319348 | 0.73 | CYP2D6 (0.45) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL8151923 | 0.72 | MEN1 (0.50) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| Carbon Monoxide SCHEMBL8145637 | 0.72 | MEN1 (0.46) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL16118506 | 0.69 | MET (0.42) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL28861190 | 0.69 | BRD4 (0.47) | BRD4MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL27784194 | 0.69 | MET (0.49) | BRD4MEN1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993204-A | Certain chemical entities, compositions and methods | CYTOKINETICS INC | 2013-03-27 | — | — | CN | claimed |
| CN-101522681-A | Specific chemical entities, compositions and methods | CYTOKINETICS INC (US) | 2009-09-02 | — | — | CN | claimed |
| CN-102993204-A | Certain chemical entities, compositions and methods | CYTOKINETICS INC | 2013-03-27 | — | — | CN | disclosed |
| CN-101522681-A | Specific chemical entities, compositions and methods | CYTOKINETICS INC (US) | 2009-09-02 | — | — | CN | disclosed |