Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23557987 | 0.84 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BDPP4TAAR1 | |
| SCHEMBL33804 | 0.81 | MAPT (0.55) | MAPTMAPK14POLBPIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL6259439 | 0.80 | MAPT (0.53) | MAPTMAPK14POLBPIK3CDPIK3CA | |
| SCHEMBL1799990 | 0.79 | ADORA2A (0.48) | ADORA2AADORA1MAPTPOLBKDM4E | |
| Benzene SCHEMBL27762704 | 0.79 | NPC1 (0.50) | ADORA2AADORA1ADORA2BDPP4TAAR1 | |
| Benzene SCHEMBL27762724 | 0.76 | ADORA1 (0.49) | ADORA2AADORA1ADORA2BDPP4MAPT | |
| SCHEMBL31632811 | 0.74 | ADORA2A (0.42) | ADORA2AADORA1ADORA2BDPP4TAAR1 | |
| SCHEMBL15428594 | 0.73 | ADCY10 (0.44) | ADORA2AADORA1ADORA2BDPP4TAAR1 | |
| SCHEMBL14075005 | 0.73 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BDPP4TAAR1 | |
| SCHEMBL13198213 | 0.73 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BDPP4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553489-A | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2009-10-07 | — | — | CN | claimed |
| CN-101553489-B | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILI | 2013-07-17 | — | — | CN | disclosed |
| CN-101553489-A | 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine derivatives, methods for their preparation and their use as antiviral agents | DRITTE PATENTPORTFOLIO BETEILI (DE) | 2009-10-07 | — | — | CN | disclosed |