Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.57 |
| ▸ | DRD3 | P35462 | 9/20 | 0.56 |
| ▸ | DRD4 | P21917 | 8/20 | 0.53 |
| ▸ | HTR1A | P08908 | 6/20 | 0.53 |
| ▸ | DRD1 | P21728 | 6/20 | 0.53 |
| ▸ | DRD5 | P21918 | 6/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 1/20 | 0.53 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973130 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL29744881 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL1342921 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL9205714 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL4697445 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL1424708 | 1.00 | DRD2 (0.57) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL27749604 | 0.80 | DRD2 (0.50) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL10274630 | 0.79 | DRD2 (0.69) | DRD2DRD3DRD4HTR1ADRD1 | |
| Ammonia Solution, Strong SCHEMBL3406155 | 0.79 | DRD2 (0.49) | DRD2DRD3DRD4HTR1ADRD1 | |
| Hydrochloric Acid SCHEMBL27854009 | 0.78 | DRD2 (0.47) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101583593-A | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof | PFIZER PROD INC (US) | 2009-11-18 | — | — | CN | disclosed |