Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314037 | 0.85 | TLR7 (0.53) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL29232872 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL13147606 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL13999764 | 0.80 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL28356710 | 0.80 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL9415800 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL9415797 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL16503356 | 0.79 | PLA2G4A (0.44) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL16503358 | 0.79 | PLA2G4A (0.44) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A | |
| SCHEMBL4885031 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4ETLR7PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842357-A | Substituted pyrazole derivatives | TAKEDA PHARMACEUTICAL | 2010-09-22 | — | — | CN | disclosed |