Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781194 | 0.87 | HSD11B1 (0.37) | ABL1PIK3CDHSD11B1 | |
| SCHEMBL27802815 | 0.85 | PIK3CD (0.45) | PIK3CDNR4A2 | |
| SCHEMBL27781205 | 0.83 | ADORA1 (0.42) | CTSA | |
| SCHEMBL27781354 | 0.83 | MBNL1 (0.40) | PIK3CDNR4A2CTSA | |
| SCHEMBL27781208 | 0.80 | PTGER1 (0.41) | PIK3CDCTSA | |
| SCHEMBL4176663 | 0.80 | PIK3CD (0.43) | ABL1PIK3CDHSD11B1NR4A2CTSA | |
| SCHEMBL27781195 | 0.78 | ABL1 (0.40) | ABL1HSD11B1 | |
| SCHEMBL27781234 | 0.77 | PIK3CD (0.40) | PIK3CDHSD11B1 | |
| SCHEMBL4174726 | 0.76 | PIK3CD (0.39) | PIK3CDMAPK14 | |
| SCHEMBL27802982 | 0.76 | DHODH (0.43) | PIK3CDNR4A2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101715453-B | Heterocyclic compounds and their uses | AMGEN INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101715453-A | Heterogeneous ring compound and application thereof | AMGEN INC | 2010-05-26 | — | — | CN | disclosed |