Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788770 | 0.86 | ALOX5 (0.45) | ALOX5HCRTR1HCRTR2 | |
| SCHEMBL14631967 | 0.78 | HCRTR1 (0.45) | ALOX5HCRTR1HCRTR2 | |
| SCHEMBL986346 | 0.77 | HCRTR1 (0.43) | ALOX5HCRTR1HCRTR2OPRM1 | |
| SCHEMBL27899608 | 0.76 | ALOX5 (0.52) | ALOX5HCRTR1HCRTR2GAA | |
| SCHEMBL981438 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2OPRM1GAASMN1; SMN2 | |
| SCHEMBL27803498 | 0.76 | ALOX5 (0.48) | ALOX5HCRTR1HCRTR2HDAC9TSHR | |
| SCHEMBL28786380 | 0.75 | ALOX5 (0.54) | ALOX5HCRTR1HCRTR2 | |
| SCHEMBL28790352 | 0.75 | ALOX5 (0.47) | ALOX5HCRTR1HCRTR2GAASMN1; SMN2 | |
| SCHEMBL28790280 | 0.75 | ALOX5 (0.73) | ALOX5GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27824202 | 0.74 | ALOX5 (0.46) | ALOX5HCRTR1HCRTR2HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-101965343-A | 2-aza-bicyclo[2.2.1]heptane derivatives | ACTELION PHARMACEUTICALS LTD | 2011-02-02 | — | — | CN | disclosed |