SCHEMBL2878672

SCHEMBL2878672

C1=C[C]2CCCCC2CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2878584 0.93
SCHEMBL12467506 0.86 ALDH1A1 (0.34) MAOAMAOBALDH1A1
SCHEMBL7783727 0.86 ALDH1A1 (0.39) MAOAMAOBALDH1A1
SCHEMBL1524983 0.86 ALDH1A1 (0.39) MAOAMAOBALDH1A1
SCHEMBL2540038 0.84 ALDH1A1 (0.36) MAOAMAOBALDH1A1
SCHEMBL166697 0.83
SCHEMBL12465603 0.82 ALDH1A1 (0.34) MAOAMAOBALDH1A1
SCHEMBL1524597 0.81
SCHEMBL19463253 0.75
SCHEMBL5066474 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183286-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA NOVARTIS AG (CH) 2023-06-15 US disclosed
EP-3904366-A1 END CAPPED NUCLEIC ACID MOLECULES Novartis AG (CH) 2021-11-03 EP disclosed
US-20200190132-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2020-06-18 US disclosed
US-10676499-B2 3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA NOVARTIS AG (CH) 2020-06-09 US disclosed
US-20180002368-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2018-01-04 US disclosed
EP-3099738-B1 POLYOLEFIN COPOLYMERS AS COLOUR IMPROVERS IN POLYAMIDES BASF SE (DE) 2017-11-29 EP disclosed
EP-3233880-A1 END CAPPED NUCLEIC ACID MOLECULES Novartis AG (CH) 2017-10-25 EP disclosed
EP-3099738-A1 POLYOLEFIN COPOLYMERS AS COLOR ENHANCERS IN POLYAMIDES BASF SE (DE) 2016-12-07 EP disclosed
US-20160340509-A1 Polyolefin Copolymers as Color Enhancers in Polyamides BASF SE (DE) 2016-11-24 US disclosed
WO-2016098028-A1 END CAPPED NUCLEIC ACID MOLECULES NOVARTIS AG (CH) 2016-06-23 WO disclosed
US-7220810-B2 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7217830-B2 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-15 US disclosed
WO-2006137840-A2 DIPHENYL ETHER ANTIMICROBIAL COMPOUNDS RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2006-12-28 WO disclosed
US-20060041025-A1 5-Alkyl (4-26 carbon atoms)-2-phenoxyphenols; enoyl reductase enzyme inhibitor; drug resistance; side-effect reduction; nicrobiocides; carriers NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-02-23 US disclosed
US-20060009600-A1 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-12 US disclosed
US-20060004219-A1 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-05 US disclosed
US-6703182-B1 PHOTOPOLYMERISABLE COMPOSITIONS COMPRISING SAID COMPOUNDS AND USE OF THE COMPOUNDS AS LATENT ACIDS, WHICH CAN BE ACTIVATED BY IRRADIATION WITH LIGHT CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-09 US disclosed
EP-1105373-B1 UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SC HOLDING AG (CH) 2002-10-09 EP disclosed
EP-1105373-A1 UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2001-06-13 EP disclosed
WO-2000010972-A1 NEW UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183286-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA RNGTT, NSUN2, NSUN3 MAOA 4538/4885MAOB 4654/4885ALDH1A1 3871/4885
US-20200190132-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA RNGTT, NSUN2, NSUN3 MAOA 4538/4885MAOB 4654/4885ALDH1A1 3871/4885
US-20180002368-A1 NOVEL 3' END CAPS, 5' END CAPS AND COMBINATIONS THEREOF FOR THERAPEUTIC RNA NSUN2, NSUN3, RNGTT MAOA 4649/4885MAOB 4757/4885ALDH1A1 4255/4885
US-20060004219-A1 Organic silicon compound and method for preparing the same AR, PKD1, SKP2 MAOA 2556/4885MAOB 2266/4885ALDH1A1 1352/4885
US-10676499-B2 3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA RNGTT, NSUN3, NSUN2 MAOA 4367/4885MAOB 4587/4885ALDH1A1 3685/4885
US-20060041025-A1 5-Alkyl (4-26 carbon atoms)-2-phenoxyphenols; enoyl reductase enzyme inhibitor; drug resistance; side-effect reduction; nicrobiocides; carriers CBR1, CBR3, FAR1 MAOA 290/4885MAOB 156/4885ALDH1A1 855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.