SCHEMBL2878708

SCHEMBL2878708

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
PPARG P37231 5/20 0.56
F7 P08709 4/20 0.56
CYP19A1 P11511 4/20 0.56
F3 P13726 4/20 0.56
PPARD Q03181 4/20 0.56
PPARA Q07869 4/20 0.56
PTGS1 P23219 3/20 0.56
KMT2A Q03164 3/20 0.56
OXER1 Q8TDS5 2/20 0.56
ADORA3 P0DMS8 2/20 0.56
RXRA P19793 1/20 0.56
TRPV1 Q8NER1 1/20 0.54
MAPT P10636 3/20 0.52
FFAR1 O14842 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
NR1I2 O75469 2/20 0.52
PTGS2 P35354 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755168 1.00 ALDH1A1 (0.56) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL23648282 1.00 ALDH1A1 (0.56) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL14612882 1.00 ALDH1A1 (0.56) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL23648284 1.00 ALDH1A1 (0.56) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL1325085 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL7845617 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL1325082 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL18489893 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL22539035 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3
SCHEMBL1325084 0.92 TRPV1 (0.64) ALDH1A1PPARGF7CYP19A1F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010508261-A 2010-03-18 JP claimed
EP-2129646-A2 OMEGA-3 LIPID COMPOUNDS Pronova Biopharma Norge AS (NO) 2009-12-09 EP claimed
WO-2008132552-A2 OMEGA-3 LIPID COMPOUNDS PRONOVA BIOPHARMA NORGE AS (US) 2008-11-06 WO claimed
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2025-11-11 US disclosed
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-05-16 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2022-09-08 US disclosed
EP-3210972-A1 METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) Catabasis Pharmaceuticals, Inc. (US) 2017-08-30 EP disclosed
WO-2017093732-A1 LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE BIOZEP AS (NO) 2017-06-08 WO disclosed
EP-2580204-B1 CYSTEAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NASH KRISANI BIOSCIENCE (P) LTD (IN) 2017-03-08 EP disclosed
WO-2009134147-A1 LIPID COMPOSITIONS CONTAINING DERIVATIVES OF EPA AND DHA AN THEIR USE THEREOF PRONOVA BIOPHARMA NORGE AS (NO) 2009-11-05 WO disclosed
WO-2008139261-A2 OMEGA-3 LIPID COMPOUND PRONOVA BIOPHARMA NORGE AS (US) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885PPARG 30/4885F7 1250/4885
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885PPARG 30/4885F7 1250/4885
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885PPARG 30/4885F7 1250/4885
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885PPARG 30/4885F7 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.