SCHEMBL2878727

SCHEMBL2878727

ClC(Cl)CCc1ccccc1CCC(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TAAR1 Q96RJ0 8/20 0.36
PNMT P11086 1/20 0.33
HTR2A P28223 1/20 0.33
TSHR P16473 1/20 0.33
IDO1 P14902 1/20 0.33
HIF1A Q16665 1/20 0.32
AKR1B1 P15121 1/20 0.31
HSPA5 P11021 1/20 0.31
AOC3 Q16853 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875222 0.84 SLC6A4 (0.36) SLC6A2SLC6A4SLC6A3TAAR1PNMT
SCHEMBL2880977 0.82 SLC6A4 (0.35) SLC6A2SLC6A4SLC6A3TAAR1PNMT
SCHEMBL4237177 0.81 ALDH1A1 (0.48) TAAR1HTR2ATSHR
SCHEMBL2869414 0.80 LIPG (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL2878749 0.80 LIPG (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL2875652 0.80 LIPG (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL5254374 0.80 TDP1 (0.48)
SCHEMBL23456399 0.77 FOLH1 (0.59) TSHRHIF1A
SCHEMBL2878724 0.77 GFER (0.36) TAAR1TSHR
SCHEMBL7630645 0.72 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed