Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790716 | 0.89 | HSD17B3 (0.52) | HSD17B3ITGB3ITGA2BSTS | |
| SCHEMBL4943117 | 0.81 | GNPAT (0.49) | HPGDSMN1; SMN2ITGB3ITGA2BGNPAT | |
| SCHEMBL4943113 | 0.81 | GNPAT (0.49) | HPGDSMN1; SMN2ITGB3ITGA2BGNPAT | |
| SCHEMBL28256323 | 0.80 | PLA2G10 (0.49) | L3MBTL1GNPATTDP1PTPN1CA2 | |
| SCHEMBL28256327 | 0.80 | PLA2G10 (0.49) | L3MBTL1GNPATTDP1PTPN1CA2 | |
| SCHEMBL2772723 | 0.78 | TDP1 (0.54) | L3MBTL1GNPATTDP1MMEACE | |
| SCHEMBL25341206 | 0.77 | PRSS1 (0.50) | ITGB3ITGA2BPTPN1CA2CA1 | |
| SCHEMBL680563 | 0.76 | SLC7A5 (0.59) | L3MBTL1CA2CA1MMEACE | |
| SCHEMBL5153319 | 0.76 | SLC7A5 (0.59) | L3MBTL1CA2CA1MMEACE | |
| SCHEMBL680562 | 0.76 | SLC7A5 (0.59) | L3MBTL1CA2CA1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987865-B | Antagonist of luteinizing hormone releasing hormone (LHRH) containing hydantoin structure | INST PHARM & TOXICOLOGY AMMS | 2014-07-30 | — | — | CN | disclosed |
| CN-101987865-A | Antagonist of luteinizing hormone releasing hormone (LHRH) containing hydantoin structure | INST PHARM & TOXICOLOGY AMMS | 2011-03-23 | — | — | CN | disclosed |