Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787374 | 0.89 | L3MBTL1 (0.51) | HSD17B3ITGB3ITGA2BSTS | |
| SCHEMBL28655370 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191870 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191872 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191869 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191876 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191878 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL13191875 | 0.79 | HSD17B3 (0.59) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL9335675 | 0.79 | HSD17B3 (0.63) | HSD17B3S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL9335705 | 0.79 | HSD17B3 (0.63) | HSD17B3S1PR5S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987865-B | Antagonist of luteinizing hormone releasing hormone (LHRH) containing hydantoin structure | INST PHARM & TOXICOLOGY AMMS | 2014-07-30 | — | — | CN | disclosed |
| CN-101987865-A | Antagonist of luteinizing hormone releasing hormone (LHRH) containing hydantoin structure | INST PHARM & TOXICOLOGY AMMS | 2011-03-23 | — | — | CN | disclosed |