SCHEMBL680563

SCHEMBL680563

NNC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.59
FOLH1 Q04609 1/20 0.56
NAALAD2 Q9Y3Q0 1/20 0.56
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
MME P08473 7/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ACE P12821 4/20 0.51
CPA1 P15085 1/20 0.51
ACE2 Q9BYF1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680562 1.00 SLC7A5 (0.59) SLC7A5FOLH1NAALAD2CA1CA2
SCHEMBL5153319 1.00 SLC7A5 (0.59) SLC7A5FOLH1NAALAD2CA1CA2
SCHEMBL8651835 0.86 SLC7A5 (0.56) SLC7A5FOLH1NAALAD2CA1CA2
SCHEMBL29486918 0.85 CA2 (0.54) SLC7A5FOLH1NAALAD2CA2MME
SCHEMBL5694618 0.85 GNPAT (0.58) SLC7A5FOLH1NAALAD2MMEL3MBTL1
SCHEMBL93439 0.85 GNPAT (0.58) SLC7A5FOLH1NAALAD2MMEL3MBTL1
SCHEMBL93440 0.85 GNPAT (0.58) SLC7A5FOLH1NAALAD2MMEL3MBTL1
SCHEMBL412958 0.85 GNPAT (0.58) SLC7A5FOLH1NAALAD2MMEL3MBTL1
SCHEMBL13464491 0.84 SLC7A5 (0.49) SLC7A5FOLH1NAALAD2CA1CA2
SCHEMBL2772723 0.84 TDP1 (0.54) FOLH1MMEKMT2AL3MBTL1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216524-A1 Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation TRUSTEES BOSTON COLLEGE (US) 2024-07-04 US claimed
EP-4035698-A1 WOUND DRESSING AND METHOD FOR PREPARING THE SAME Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-08-03 EP claimed
US-20210220298-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING METABOLIC SYNDROME INDUCED BY ANTIPSYCHOTIC TREATMENT AND RELATED DISEASES AND CONDITIONS TUFTS MEDICAL CENTER, INC. 2021-07-22 US claimed
CN-112516057-A Composite biological scar-removing factor nutritional scar-removing whitening cream and preparation method thereof 郑楠 2021-03-19 CN claimed
US-20180360984-A1 Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation TRUSTEES OF BOSTON COLLEGE 2018-12-20 US claimed
CN-102224238-B Non-natural amino acid replication-dependent microorganisms and vaccines AMBRX INC 2015-06-10 CN claimed
US-8969288-B2 Amide based glucagon and superfamily peptide prodrugs INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-03-03 US claimed
CN-103864892-A Peptide tyrosinase inhibitors and uses thereof UNIV LELAND STANFORD JUNIOR 2014-06-18 CN claimed
CN-102203257-B 3-amino tyrosine genetic incorporation of reductases SCRIPPS RESEARCH INST 2014-01-08 CN claimed
CN-102369210-A Antibacterial peptide AMP THERAPEUTICS GMBH & CO KG 2012-03-07 CN claimed
CN-101970005-A Breaking immunological tolerance with a genetically encoded unnatural amino acid SCRIPPS RESEARCH INST 2011-02-09 CN claimed
WO-2010071807-A1 AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2010-06-24 WO claimed
US-20030165983-A1 Proteomic determination of protein nitrotyrosine modifications using mass spectrometry REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2003-09-04 US claimed
WO-2001084160-A2 PROTEOMIC DETERMINATION OF PROTEIN NITROTYROSINE MODIFICATIONS USING MASS SPECTROMETRY MITOKOR (US) 2001-11-08 WO claimed
EP-0785921-B1 PROCESS FOR PRODUCING SODIUM 1-THYROXINE COMPRISING THE OXIDATIVE COUPLING OF A DIIDO-1-TYROSINE CATALYSED BY A MANGANESE SALT IN THE PRESENCE OF AN AMINE KNOLL AG (DE) 2000-04-26 EP claimed
US-5384116-A Synthetic melanin as a sunscreen and tanning agent YALE UNIVERSITY (US) 1995-01-24 US claimed
EP-0089365-A4 New Dye or Fluorescent polymers and their use as labels in immunoassay systems. HENRY ROBERT P 1985-08-21 EP claimed
US-4452886-A Novel photon absorbing or emitting polymers and their use as reagents in immunoassay systems PHOTEST DIAGNOSTICS, INC. A CORPORATION OF DE 1984-06-05 US claimed
EP-0089365-A1 New Dye or Fluorescent polymers and their use as labels in immunoassay systems. PHOTEST DIAGNOSTICS, INC. (US) 1983-09-28 EP claimed
WO-1983001064-A1 NOVEL PHOTON ABSORBING OR EMITTING POLYMERS AND THEIR USE AS REAGENTS IN IMMUNOASSAY SYSTEMS HENRY, ROBERT, P. 1983-03-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210220298-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING METABOLIC SYNDROME INDUCED BY ANTIPSYCHOTIC TREATMENT AND RELATED DISEASES AND CONDITIONS GPR119, PC, NLN SLC7A5 4169/4885FOLH1 3730/4885NAALAD2 2857/4885
US-20240216524-A1 Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation PAICS, DNPEP, ABCG2 SLC7A5 127/4885FOLH1 712/4885NAALAD2 18/4885
US-20180360984-A1 Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation PAICS, DNPEP, ABCG2 SLC7A5 127/4885FOLH1 712/4885NAALAD2 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.