Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL6940297 | 1.00 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL1096735 | 0.97 | ALDH1A1 (0.78) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL2309223 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL948368 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL1816268 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL8145547 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL6066779 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL15546159 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL15443206 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL18492853 | 0.97 | ALDH1A1 (0.88) | ALDH1A1LMNAHSD17B10TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116555102-B | Lactobacillus plantarum producing gamma-aminobutyric acid, sleep-aiding probiotic composition and preparation method thereof | 江苏新申奥生物科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116555102-A | Lactobacillus plantarum producing gamma-aminobutyric acid, sleep-aiding probiotic composition and preparation method thereof | 江苏新申奥生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-112710797-B | Quality detection method for cough and asthma relieving pharmaceutical composition | 贵州大隆药业有限责任公司 | 2023-04-07 | — | — | CN | claimed |
| CN-112710797-A | Quality detection method for cough and asthma relieving pharmaceutical composition | 贵州大隆药业有限责任公司 | 2021-04-27 | — | — | CN | claimed |
| CN-106565749-B | The method for promoting Cefamandole Nafate quality using three-dimensional column plate purification solvent | 华北制药河北华民药业有限责任公司 | 2018-10-09 | — | — | CN | claimed |
| CN-106565749-A | Method for improving quality of cemandil sodium by using three-dimensional column plate to purify solvent | 华北制药河北华民药业有限责任公司 | 2017-04-19 | — | — | CN | claimed |
| CN-116555102-B | Lactobacillus plantarum producing gamma-aminobutyric acid, sleep-aiding probiotic composition and preparation method thereof | 江苏新申奥生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116555102-A | Lactobacillus plantarum producing gamma-aminobutyric acid, sleep-aiding probiotic composition and preparation method thereof | 江苏新申奥生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-112710797-B | Quality detection method for cough and asthma relieving pharmaceutical composition | 贵州大隆药业有限责任公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-4021892-A1 | SPHINGOLIPID-BASED SELENIUM COMPOUNDS, METHODS FOR THEIR PREPARATION, AND PHARMACEUTICAL USES THEREOF, INCLUDING AS ANTITUMOR AGENTS | Musc Foundation for Research Development (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-112710797-A | Quality detection method for cough and asthma relieving pharmaceutical composition | 贵州大隆药业有限责任公司 | 2021-04-27 | — | — | CN | disclosed |
| WO-2021041825-A1 | SPHINGOLIPID-BASED SELENIUM COMPOUNDS, METHODS FOR THEIR PREPARATION, AND PHARMACEUTICAL USES THEREOF, INCLUDING AS ANTITUMOR AGENTS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2021-03-04 | — | — | WO | disclosed |
| US-20190241557-A1 | COMPOSITIONS AND USES THEREOF | PLEXXIKON INC. | 2019-08-08 | — | — | US | disclosed |
| CN-1047869-A | The acylated derivatives of etoposide | BRISTOL MYERS SQUIBB CO (US) | 1990-12-19 | — | — | CN | disclosed |
| EP-0401800-A2 | Acylated derivatives of etoposide | Bristol-Myers Squibb Company (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4751246-A | ALPHA(AMINOALKYL)-4-HYDROXY-3-(ALKYLSULFINYL) BENZENEMETHANOL AND 2-(4-HYDROXY-3-(ALKYLSULFINYL) PHENYL)ETHYLAMINE-HYPOTENSIVE AGENTS | STERLING DRUG INC. (US) | 1988-06-14 | — | — | US | disclosed |
| US-4452816-A | HYPOTENSIVE AND ANTIARRHYTHMIA AGENTS | STERLING DRUG INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4374149-A | HYPOTENSIVE AGENT AND VASODILATOR | STERLING DRUG INC. (US) | 1983-02-15 | — | — | US | disclosed |
| US-4255564-A | ANTIBIOTICS, PROTECTED ALDEHYDE GROUP, INTERMEDIATES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4196280-A | Novel macrolactone derivatives and process of producing them | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241557-A1 | COMPOSITIONS AND USES THEREOF | SFPQ, PML, PRNP | ALDH1A1 1269/4885LMNA 1226/4885HSD17B10 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.