Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246008 | 0.88 | PLA2G4A (0.55) | PLA2G4ASLC6A3ECE1KDM4EMAPT | |
| SCHEMBL13447428 | 0.86 | DPP4 (0.41) | PLA2G4ASLC6A3ECE1KDM4EMAPT | |
| SCHEMBL3698353 | 0.83 | PLA2G4A (0.57) | PLA2G4AECE1KDM4EMAPTCYP1A2 | |
| SCHEMBL2142396 | 0.82 | RAB9A (0.57) | PLA2G4AMAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL27867999 | 0.81 | PLA2G4A (0.60) | PLA2G4AECE1KDM4EHCAR3HCAR2 | |
| SCHEMBL3549517 | 0.81 | PLA2G4A (0.60) | PLA2G4AECE1KDM4EHCAR3HCAR2 | |
| SCHEMBL1837764 | 0.81 | ECE1 (0.44) | PLA2G4ASLC6A3ECE1KDM4EHSP90AA1 | |
| SCHEMBL13587127 | 0.81 | ECE1 (0.45) | PLA2G4ASLC6A3ECE1MAPTNPC1 | |
| SCHEMBL27885973 | 0.81 | RAB9A (0.40) | PLA2G4ASLC6A3KDM4EMAPTNPC1 | |
| SCHEMBL29287225 | 0.80 | ECE1 (0.46) | PLA2G4AECE1KDM4EHSP90AA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |