Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539136 | 0.84 | FFAR1 (0.45) | FFAR1NPC1RAB9AL3MBTL1GAA | |
| SCHEMBL4415483 | 0.84 | LMNA (0.58) | FFAR1GAALMNATSHR | |
| SCHEMBL24883421 | 0.83 | LMNA (0.44) | FFAR1GAALMNATSHRSMN1; SMN2 | |
| SCHEMBL24883415 | 0.83 | PPARA (0.52) | FFAR1NPC1RAB9AGAAMAPT | |
| SCHEMBL1544953 | 0.82 | FFAR1 (0.53) | FFAR1NPC1RAB9AL3MBTL1IKBKB | |
| Hydrochloric Acid SCHEMBL1374005 | 0.82 | LMNA (0.57) | FFAR1GAALMNATSHR | |
| SCHEMBL4944035 | 0.82 | FFAR1 (0.53) | FFAR1NPC1RAB9AL3MBTL1IKBKB | |
| SCHEMBL21357696 | 0.81 | FFAR1 (0.51) | FFAR1NPC1RAB9AL3MBTL1IKBKB | |
| SCHEMBL5117052 | 0.79 | HDAC1 (0.56) | FFAR1GAALMNATP53TSHR | |
| SCHEMBL2868465 | 0.78 | ADRB2 (0.55) | FFAR1NPC1RAB9AL3MBTL1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101723941-A | “1,2,4” oxadiazole as a metabotropic glutamate receptor-5 modulator | ASTRAZENECA AB | 2010-06-09 | — | — | CN | disclosed |