Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.75 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.75 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.75 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.75 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.75 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.75 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.71 |
| ▸ | RAD52 | P43351 | 3/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | EGFR | P00533 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL382846 | 0.95 | ACHE (0.82) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL18062500 | 0.95 | ACHE (0.82) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL21561417 | 0.93 | RAD52 (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL18062501 | 0.93 | ACHE (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL11504012 | 0.93 | ACHE (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| SCHEMBL34882 | 0.93 | ACHE (0.81) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Formaldehyde SCHEMBL28001350 | 0.91 | ACHE (0.71) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL28870412 | 0.91 | ACHE (0.75) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Water SCHEMBL2150838 | 0.90 | ACHE (0.77) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL2696916 | 0.90 | ACHE (0.77) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131527-B | Polyelectrolyte complexes for imparting antimicrobial properties to substrates | QUICK MED TECHNOLOGIES INC | 2014-11-26 | — | — | CN | disclosed |
| CN-102131527-A | Polyelectrolyte complexes for imparting antimicrobial properties to substrates | QUICK MED TECHNOLOGIES INC | 2011-07-20 | — | — | CN | disclosed |