Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.82 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.82 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.82 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.82 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.82 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.82 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.77 |
| ▸ | RAD52 | P43351 | 3/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.82 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.82 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | EGFR | P00533 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.82 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18062500 | 1.00 | ACHE (0.82) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL18062501 | 0.97 | ACHE (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL21561417 | 0.97 | RAD52 (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL11504012 | 0.97 | ACHE (0.78) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| SCHEMBL34882 | 0.97 | ACHE (0.81) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Bromide SCHEMBL28870412 | 0.95 | ACHE (0.75) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Ethylene SCHEMBL28788397 | 0.95 | ACHE (0.75) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Water SCHEMBL2150838 | 0.95 | ACHE (0.77) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL2696916 | 0.95 | ACHE (0.77) | ACHERAD52HSP90AA1CHRM2ADRA2A | |
| Fluoride Ion SCHEMBL1502795 | 0.95 | ACHE (0.77) | ACHERAD52HSP90AA1CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1041 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735622-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | Illumina, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| CN-117126654-B | Blocking remover, preparation method, use method and application | 中国石油天然气股份有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119823109-A | An electrochromic material electrochromic composition and electrochromic device | 吉林大学 | 2025-04-15 | — | — | CN | claimed |
| WO-2025003459-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | ILLUMINA, INC. (US) | 2025-01-02 | — | — | WO | claimed |
| EP-4371653-A1 | FABRICATION OF FILTRATION MEMBRANES | Trustees of Tufts College (US) | 2024-05-22 | — | — | EP | claimed |
| EP-3470493-B1 | COMPOSITIONS COMPRISING LATENT HEAT STORAGE MATERIALS | PHASE CHANGE ENERGY SOLUTIONS INC (US) | 2024-05-15 | — | — | EP | claimed |
| WO-2024081696-A2 | COMPOSITIONS CONTAINING PHASE CHANGE MATERIALS, METHODS FOR FORMING OBJECTS USING THE SAME, AND METHOD FOR USING THE SAME | PHASE CHANGE ENERGY SOLUTIONS, INC. (US) | 2024-04-18 | — | — | WO | claimed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | claimed |
| US-20240021887-A1 | ELECTROLYTE FOR AQUEOUS ZINC-BROMINE BATTERY CONTAINING BROMINE COMPLEXING AGENT AND METAL ION ADDITIVE, AND AQUEOUS ZINC-BROMINE NON-FLOW BATTERY CONTAINING SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-01-18 | — | — | US | claimed |
| CN-117126654-A | Blocking remover, preparation method, use method and application | 中国石油天然气股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| US-20040005286-A1 | Organic salt conditioner, organic salt-containing composition, and uses thereof | L'OREAL (FR) | 2004-01-08 | — | — | US | claimed |
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | claimed |
| US-6579343-B2 | Contacting gas with a liquid ionic compound comprising a nitrogen-containing heterocyclic cation | UNIVERSITY OF NOTRE DAME DU LAC | 2003-06-17 | — | — | US | claimed |
| US-20020189444-A1 | Purification of gas with liquid ionic compounds | NATIONAL SCIENCE FOUNDATION | 2002-12-19 | — | — | US | claimed |
| EP-1183016-A1 | STEREOCOMPLEX HYDROGELS | Universiteit Utrecht (NL) | 2002-03-06 | — | — | EP | claimed |
| WO-2000048576-A1 | STEREOCOMPLEX HYDROGELS | UNIVERSITEIT UTRECHT (NL) | 2000-08-24 | — | — | WO | claimed |
| US-5356748-A | Nonaqueous solvent containing dispersed resin grains and graft polymer stabilizer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-18 | — | — | US | claimed |
| EP-0272674-B1 | PROCESS FOR PRODUCING 2,6-DICHLOROBENZYL ALCOHOL | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | claimed |
| US-4822924-A | REACTING 2,6-DICHLOROBENZYL CHLORIDE WITH SODIUM ACETATE, THEN HYDROLYZING; QUATERNARY AMMONIUM SALTS AS PHASE TRANSFER AGENTS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| EP-0272674-A2 | Process for producing 2,6-dichlorobenzyl alcohol | HODOGAYA CHEMICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005286-A1 | Organic salt conditioner, organic salt-containing composition, and uses thereof | KRT18, HCN4, PRKDC | ACHE 2144/4885CHRM2 3434/4885CHRM1 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.