Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NPR1 | P16066 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876357 | 0.88 | CYP2E1 (0.42) | MKNK1CHEK1HDAC1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL2874873 | 0.87 | CYP2E1 (0.41) | MKNK1CHEK1HDAC1KDM4EHTT | |
| SCHEMBL2870751 | 0.86 | KDM4E (0.47) | MKNK1KDM4EHTTATMCHRM3 | |
| SCHEMBL14030874 | 0.86 | MKNK1 (0.37) | MKNK1CHEK1HDAC1KDM4EHTT | |
| SCHEMBL3807589 | 0.84 | MKNK1 (0.39) | MKNK1CHEK1KDM4EHTTATM | |
| SCHEMBL2878325 | 0.84 | HTT (0.36) | KDM4EHTTATMUSP30 | |
| SCHEMBL2157834 | 0.80 | CYP2E1 (0.43) | KDM4EHTTATMUSP30PKM | |
| SCHEMBL2877042 | 0.79 | NR1I2 (0.41) | CHEK1KDM4EHTTATM | |
| SCHEMBL3812146 | 0.79 | KDM4E (0.41) | KDM4EHTTATMUSP30 | |
| SCHEMBL2881334 | 0.79 | CPB1 (0.42) | KDM4EHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |