Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879462 | 0.90 | CYP3A4 (0.52) | CPB1CYP3A4LMNAMAPTSLC2A1 | |
| SCHEMBL3811557 | 0.89 | CPB1 (0.49) | CPB1CYP3A4LMNASMN1; SMN2NR1H4 | |
| SCHEMBL2878988 | 0.88 | CPB1 (0.43) | CPB1CYP3A4LMNASMN1; SMN2MAPT | |
| SCHEMBL2881336 | 0.86 | SMN1; SMN2 (0.40) | CPB1CYP3A4LMNASMN1; SMN2HTT | |
| SCHEMBL3811469 | 0.85 | CPB1 (0.43) | CPB1NR1H4HTTMEN1KMT2A | |
| SCHEMBL3807405 | 0.85 | CPB1 (0.43) | CPB1CYP3A4SMN1; SMN2NR1H4HTT | |
| SCHEMBL3811147 | 0.85 | CPB1 (0.47) | CPB1CYP3A4LMNASMN1; SMN2NR1H4 | |
| SCHEMBL3808984 | 0.84 | KDM4E (0.37) | CYP3A4CYP19A1MAPTABHD6HTT | |
| SCHEMBL3815298 | 0.84 | CPB1 (0.41) | CPB1NR1H4MEN1KMT2A | |
| SCHEMBL3811131 | 0.82 | NR1H4 (0.49) | CPB1CYP3A4NR1H4MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |