Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP1 | P63208 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825610 | 0.88 | TP53 (0.45) | GPR119ACHELMNATLR9TLR7 | |
| SCHEMBL27805021 | 0.85 | HPGD (0.39) | KDM4EHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27805098 | 0.84 | PLD1 (0.47) | KDM4EHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28786866 | 0.83 | DDB1 (0.39) | GPR119HTTACHELMNATLR9 | |
| SCHEMBL27825615 | 0.83 | DDB1 (0.39) | GPR119HTTACHELMNATLR9 | |
| SCHEMBL1123719 | 0.82 | GPR119 (0.56) | GPR119CKS1BSKP1SKP2KDM4E | |
| SCHEMBL27804993 | 0.77 | PLD1 (0.39) | KDM4EHTTACHELMNAALDH1A1 | |
| SCHEMBL30516861 | 0.74 | GPR119 (0.79) | GPR119CKS1BSKP1SKP2KDM4E | |
| SCHEMBL1459701 | 0.74 | GPR119 (0.79) | GPR119CKS1BSKP1SKP2KDM4E | |
| SCHEMBL27804976 | 0.73 | MAPT (0.39) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |