SCHEMBL30516861

SCHEMBL30516861

CC(C)(C)OC(=O)N1CCN(c2ccccn2)CC1

nearest known ligand 0.79

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.79
CKS1B P61024 2/20 0.61
SKP1 P63208 2/20 0.61
SKP2 Q13309 2/20 0.61
ALDH1A1 P00352 6/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HSD17B10 Q99714 4/20 0.57
TSHR P16473 3/20 0.57
CYP2C19 P33261 2/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
KDM4E B2RXH2 4/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C9 P11712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459701 1.00 GPR119 (0.79) GPR119CKS1BSKP1SKP2ALDH1A1
SCHEMBL29461612 0.95 GPR119 (0.72) GPR119CKS1BSKP1SKP2ALDH1A1
SCHEMBL4823523 0.95 GPR119 (0.72) GPR119CKS1BSKP1SKP2ALDH1A1
SCHEMBL29461540 0.92 GPR119 (0.76) GPR119CKS1BSKP1SKP2ALDH1A1
SCHEMBL3487749 0.89 GPR119 (1.00) GPR119
SCHEMBL29461577 0.89 HSD17B10 (0.76) GPR119ALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL27090945 0.86 GPR119 (0.68) GPR119CKS1BSKP1SKP2ALDH1A1
SCHEMBL29461422 0.85 GPR119 (0.66) GPR119ALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL29461735 0.85 HSD17B10 (0.76) GPR119ALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL2755874 0.84 HSD17B10 (0.78) ALDH1A1SMN1; SMN2HSD17B10TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025029897-A1 SUBSTITUTED PYRAZOLOPYRIDINES NEURO3 THERAPEUTICS, INC. (US) 2025-02-06 WO disclosed
WO-2023088477-A1 MULTIFUNCTIONAL COMPOUND CAPABLE OF DEGRADING BTK KINASE, AND COMPOSITION AND USE 杭州和正医药有限公司 2023-05-25 WO disclosed