Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 5/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190010 | 1.00 | MEN1 (0.39) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL25264499 | 1.00 | MEN1 (0.39) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL17227883 | 0.85 | NFKB1 (0.38) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL17229229 | 0.85 | NFKB1 (0.38) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL725410 | 0.85 | NFKB1 (0.38) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL30315348 | 0.85 | NFKB1 (0.38) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL17227902 | 0.84 | MAOB (0.40) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL25201323 | 0.84 | MAOB (0.40) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL15954244 | 0.84 | MAOB (0.40) | MEN1KMT2ANFKB1NFKB2RELA | |
| SCHEMBL25193070 | 0.83 | POLB (0.39) | MEN1KMT2ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101921252-B | 1-oxa-benzo-heterocycle compound, synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-05-09 | — | — | CN | disclosed |
| CN-101921252-A | 1-oxa-benzo-heterocycle compound, synthesis method and application thereof | SHANGHAI INST ORGANIC CHEM | 2010-12-22 | — | — | CN | disclosed |