Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829609 | 0.99 | RPS6KB1 (0.46) | MAPK14RPS6KB1FFAR2SMN1; SMN2LDHA | |
| SCHEMBL27829685 | 0.97 | MAPK14 (0.44) | MAPK14RPS6KB1FFAR2SMN1; SMN2LDHA | |
| SCHEMBL19710761 | 0.82 | MAPK14 (0.57) | MAPK14FFAR2SMN1; SMN2LCKNPC1 | |
| SCHEMBL27848060 | 0.72 | HDAC3 (0.44) | FFAR2SMN1; SMN2GSK3BNPC1GAA | |
| SCHEMBL1983871 | 0.71 | SMYD3 (0.46) | SMN1; SMN2P2RX7MAPK1 | |
| SCHEMBL28794133 | 0.71 | HDAC3 (0.46) | SMN1; SMN2GSK3BNPC1GAARAB9A | |
| SCHEMBL6387608 | 0.71 | OGA (0.43) | SMN1; SMN2P2RX7LCK | |
| SCHEMBL6393787 | 0.71 | OGA (0.43) | SMN1; SMN2P2RX7LCK | |
| SCHEMBL3129613 | 0.71 | RAB9A (0.58) | MAPK14FFAR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1985456 | 0.70 | JAK2 (0.46) | P2RX7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101918383-A | N-cycloalkylmethyl-2-aminothiazole-5-carboxamides for controlling plant diseases | SUMITOMO CHEMICAL CO | 2010-12-15 | — | — | CN | disclosed |